Herbert A Schmid Selected Research

pasireotide

1/2022	Somatostatin analogue pasireotide (SOM230) inhibits catecholamine secretion in human pheochromocytoma cells.
1/2021	Pharmacologic Normalization of Pancreatic Cancer-Associated Fibroblast Secretome Impairs Prometastatic Cross-Talk With Macrophages.
10/2018	Radiotherapy and pasireotide treatment of a growth hormone producing pituitary tumor in a diabetic dog.
1/2018	Pasireotide treatment does not modify hyperglycemic and corticosterone acute restraint stress responses in rats.
11/2016	Octreotide and pasireotide (dis)similarly inhibit pituitary tumor cells in vitro.
7/2016	Effect of pasireotide on glucose- and growth hormone-related biomarkers in patients with inadequately controlled acromegaly.
1/2016	Pasireotide Therapy of Multiple Endocrine Neoplasia Type 1-Associated Neuroendocrine Tumors in Female Mice Deleted for an Men1 Allele Improves Survival and Reduces Tumor Progression.
8/2015	Osilodrostat (LCI699), a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats.
6/2014	Lung volume quantified by MRI reflects extracellular-matrix deposition and altered pulmonary function in bleomycin models of fibrosis: effects of SOM230.
1/2014	SOM230: a new therapeutic modality for Cushing's disease.

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Herbert A Schmid Research Topics

Disease

10	Neoplasms (Cancer) 01/2022 - 01/2004
6	Acromegaly 10/2018 - 02/2006
6	Pituitary ACTH Hypersecretion 01/2014 - 05/2008
5	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2016 - 01/2004
4	Pituitary Neoplasms (Pituitary Adenoma) 10/2018 - 03/2007
3	Carcinoid Tumor (Carcinoid) 02/2009 - 01/2004
2	Hyperglycemia 01/2018 - 01/2012
2	Multiple Endocrine Neoplasia Type 1 01/2016 - 12/2012
2	Body Weight (Weight, Body) 09/2015 - 08/2015
2	ACTH-Secreting Pituitary Adenoma 01/2011 - 08/2005
1	Pheochromocytoma 01/2022
1	Adenocarcinoma 01/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Multiple Endocrine Neoplasia (Multiple Endocrine Adenomatosis) 01/2016
1	Hypertrophy 08/2015
1	Emphysema 06/2014
1	Fibrosis (Cirrhosis) 06/2014
1	Edema (Dropsy) 06/2014
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 06/2014
1	Primitive Neuroectodermal Tumors (PNET) 12/2012
1	Insulinoma 12/2012
1	Endocrine System Diseases (Endocrine Diseases) 01/2012
1	Adenoma (Adenomas) 01/2011
1	Radiation Injuries (Radiation Sickness) 06/2009
1	Prolactinoma (Prolactinomas) 05/2007
1	Obesity 06/2005
1	Prader-Willi Syndrome (Syndrome, Prader-Willi) 06/2005
1	Diarrhea 01/2004
1	Flushing 01/2004
1	Hypoglycemia (Reactive Hypoglycemia) 05/2003
1	AIDS-Related Complex (ARC) 05/2003

Drug/Important Bio-Agent (IBA)

20	pasireotideIBA 01/2022 - 01/2004
11	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2022 - 08/2005
10	Octreotide (Sandostatin)FDA LinkGeneric 01/2022 - 01/2004
7	Somatostatin Receptors (Somatostatin Receptor)IBA 11/2013 - 01/2004
5	Hormones (Hormone)IBA 01/2012 - 05/2003
4	Growth Hormone (Somatotropin)IBA 10/2018 - 01/2004
3	Glucose (Dextrose)FDA LinkGeneric 01/2018 - 12/2012
3	lanreotide (Somatuline)FDA Link 07/2016 - 01/2004
3	Adrenocorticotropic Hormone (ACTH)FDA Link 01/2011 - 08/2005
3	Insulin-Like Growth Factor I (IGF-1)IBA 05/2008 - 01/2004
2	Therapeutic UsesIBA 06/2014 - 01/2011
2	Monoclonal AntibodiesIBA 11/2013 - 01/2012
2	somatostatin receptor 2IBA 01/2012 - 01/2012
2	LigandsIBA 07/2011 - 03/2007
2	Pro-Opiomelanocortin (Proopiomelanocortin)IBA 01/2011 - 05/2003
2	GhrelinIBA 06/2005 - 05/2003
1	Nicotine FDA Link 01/2022
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 01/2022
1	CalciumIBA 01/2022
1	Carbon Fiber (Grafil)IBA 01/2022
1	CatecholaminesIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2021
1	Macrophage Colony-Stimulating FactorIBA 01/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021
1	CorticosteroneIBA 01/2018
1	GlucocorticoidsIBA 01/2018
1	Biomarkers (Surrogate Marker)IBA 07/2016
1	OsilodrostatIBA 08/2015
1	indium-bleomycinIBA 06/2014
1	Bleomycin (Blenoxane)FDA LinkGeneric 06/2014
1	Glucagon (Glukagon)FDA Link 01/2012
1	somatostatin receptor type 1IBA 01/2012
1	Insulin (Novolin)FDA Link 01/2012
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2011
1	CreatinineIBA 01/2011
1	CytokinesIBA 06/2009
1	Dopamine Agents (Dopaminergic Agents)IBA 05/2007
1	ProlactinIBA 05/2007
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2007
1	Messenger RNA (mRNA)IBA 08/2005
1	Ghrelin ReceptorsIBA 05/2003
1	Appetite Depressants (Anorectics)IBA 05/2003
1	alpha-MSHIBA 05/2003
1	Peptides (Polypeptides)IBA 05/2003
1	LeptinIBA 05/2003

Therapy/Procedure

4	Therapeutics 01/2016 - 03/2007
1	Radiotherapy 10/2018